Sex and Tamoxifen confound murine experimental studies in cardiovascular tissue engineering

Sex and Tamoxifen confound murine experimental studies in cardiovascular tissue engineering

Abstract Tissue engineered vascular grafts hold promise for the creation of functional blood vessels from biodegradable scaffolds. Because the precise mechanisms regulating this process are still under investigation, inducible genetic mouse models are an important and widely used research tool. Howe...

Full description

Bibliographic Details
Main Authors:	Kevin M. Blum, Lauren C. Roby, Jacob C. Zbinden, Yu-Chun Chang, Gabriel J. M. Mirhaidari, James W. Reinhardt, Tai Yi, Jenny C. Barker, Christopher K. Breuer
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-04-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-021-87006-3

Similar Items

Tamoxifen reduces silicone implant capsule formation in a mouse model
by: Kevin M. Blum, et al.
Published: (2022-10-01)

13. Tamoxifen Reduces the Foreign Body Response to Silicone Implants in a Mouse Model
by: Jenny C. Barker, MD, PhD, et al.
Published: (2022-06-01)

QS10: The Lysosomal Trafficking Regulator (LYST) Protein is a Novel and Essential Mediator of Cutaneous Wound Healing
by: Jenny C. Barker, M.D., Ph.D., et al.
Published: (2021-07-01)

QS57. The Lysosomal Trafficking Regulator (lyst) Gene is Regulated Through Fgf-2 Via Fgf Receptor Mediated Signaling
by: Gabriel Mirhaidari, PhD, et al.
Published: (2022-06-01)

Breast Cancer Hormone Therapy Modulates Breast Implant Capsular Contracture
by: Mehak Chawla, et al.
Published: (2023-10-01)

Confounds in neuroimaging: A clear case of sex as a confound in brain-based prediction
by: Kenneth A. Weber, et al.
Published: (2022-12-01)

Tamoxifen therapy in a murine model of myotubular myopathy
by: Nika Maani, et al.
Published: (2018-11-01)

Handling stress may confound murine gut microbiota studies
by: Cary R. Allen-Blevins, et al.
Published: (2017-01-01)

Minimizing confounders and increasing data quality in murine models for studies of the gut microbiome
by: Jun Miyoshi, et al.
Published: (2018-07-01)

Confounders in Identification and Analysis of Inflammatory Biomarkers in Cardiovascular Diseases
by: Qurrat Ul Ain, et al.
Published: (2021-10-01)

Hypertriglyceridemia and cardiovascular risk: a cautionary note about metabolic confounding
by: Allan D. Sniderman, et al.
Published: (2018-01-01)

POS-727 Surgical complications and cardiovascular comorbidity : confounders of survival after kidney transplantation
by: C. IMEN, et al.
Published: (2021-04-01)

Misspecification of confounder-exposure and confounder-outcome associations leads to bias in effect estimates
by: Noah A. Schuster, et al.
Published: (2023-01-01)

Confounding is not the only bias influencing associations of adiposity with cardiovascular disease
by: Staplin, ND
Published: (2018)

Placental Transcriptome Profiling in Subtypes of Diabetic Pregnancies Is Strongly Confounded by Fetal Sex
by: Sarah M. Kedziora, et al.
Published: (2022-12-01)

Confounding by pre-morbid functional status in studies of apparent sex differences in severity and outcome of stroke
by: Renoux, C, et al.
Published: (2017)

Endometrial thickness in tamoxifen-treated women
by: Yiu-Tai Li, et al.
Published: (2023-11-01)

Variation in use of adjuvant tamoxifen.
by: Davies, C, et al.
Published: (1998)

Confounding explanations....
by: Dunbar, R
Published: (2001)

Confounding and control
by: Guillaume Wunsch
Published: (2007-02-01)

A Reconsideration Of Tamoxifen Use for Breast Cancer
by: Peng-Hui Wang, et al.
Published: (2007-06-01)

Adjustment for continuous confounders: an example of how to prevent residual confounding.
by: Groenwold, R, et al.
Published: (2013)

Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study.
by: Bryony L Hayes, et al.
Published: (2022-01-01)

Use of antipsychotics with tamoxifen
by: H. Ghabi, et al.
Published: (2021-04-01)

It is important to control for confounders when examining the role of diet in cardiovascular disease prevention
by: Sevket Balta, et al.
Published: (2013-04-01)

Autoimmune progesterone dermatitis responding to Tamoxifen.
by: Stephens, C, et al.
Published: (1989)

A novel method for controlling unobserved confounding using double confounders
by: Lu Liu, et al.
Published: (2020-07-01)

Adjustment for unmeasured confounding through informative priors for the confounder-outcome relation
by: Rolf H. H. Groenwold, et al.
Published: (2018-12-01)

Community confounding in joint species distribution models
by: Justin J. Van Ee, et al.
Published: (2022-07-01)

Untangling the confounded relationship between perceiver sex and walker sex on the bistable perception of emotion displaying point-light walkers
by: Shaun Halovic
Published: (2023-09-01)

Bias attenuation results for dichotomization of a continuous confounder
by: Gabriel Erin E., et al.
Published: (2022-12-01)

Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania
by: Cristiana T. Trinconi, et al.
Published: (2018-12-01)

Confounded exposure metrics
by: Matthew R. Wiens, et al.
Published: (2024-02-01)

Confounding Borders and Walls
by: Natália Corazza Padovani
Published: (2014-01-01)

Confounds in “Failed” Replications
by: Paola Bressan
Published: (2019-09-01)

Resuming Sensitivity of Tamoxifen-Resistant Breast Cancer Cells to Tamoxifen by Tetrandrine
by: Yuntao Wang MS, et al.
Published: (2021-03-01)

Construct Confounding Among Predictors of Mathematics Achievement
by: Katerina Schenke, et al.
Published: (2016-05-01)

Statistically Controlling for Confounding Constructs Is Harder than You Think.
by: Jacob Westfall, et al.
Published: (2016-01-01)

Tamoxifen in horses: pharmacokinetics and safety study
by: Gonzalo Gajardo, et al.
Published: (2019-06-01)

Adjuvant chemotherapy plus tamoxifen compared with tamoxifen alone for postmenopausal breast cancer: meta-analysis of quality-adjusted survival.
by: Gelber, R, et al.
Published: (1996)