The central role of AMP-kinase and energy homeostasis impairment in Alzheimer's disease: a multifactor network analysis.

Alzheimer's disease is the most common cause of dementia worldwide, affecting the elderly population. It is characterized by the hallmark pathology of amyloid-β deposition, neurofibrillary tangle formation, and extensive neuronal degeneration in the brain. Wealth of data related to Alzheimer�...

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Bibliographic Details
Main Authors: Laura Caberlotto, Mario Lauria, Thanh-Phuong Nguyen, Marco Scotti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827084?pdf=render