Curcumin protects rat liver from streptozotocin-induced diabetic pathophysiology by counteracting reactive oxygen species and inhibiting the activation of p53 and MAPKs mediated stress response pathways

Curcumin protects rat liver from streptozotocin-induced diabetic pathophysiology by counteracting reactive oxygen species and inhibiting the activation of p53 and MAPKs mediated stress response pathways

Curcumin (CUR) is a highly pleiotropic molecule and possesses anti-inflammatory, hypoglycemic, antioxidative, wound-healing and antimicrobial activities. The present study was carried out to investigate whether CUR plays any beneficial role in streptozotocin (STZ) induced hepatic pathophysiology in...

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Bibliographic Details
Main Authors: Shatadal Ghosh, Sudip Bhattacharyya, Kahkashan Rashid, Parames C. Sil
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
Streptozotocin
Diabetes
Liver
Reactive oxygen species
Apoptosis
Curcumin
Antioxidant
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014001711

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http://www.sciencedirect.com/science/article/pii/S2214750014001711

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