Towards an integrative computational model of the guinea pig cardiac myocyte
The local control theory of excitation-contraction (EC) coupling asserts that regulation of calcium (Ca2+) release occurs at the nanodomain level, where openings of single L-type Ca2+ channels (LCCs) trigger openings of small clusters of ryanodine receptors (RyRs) co-localized within the dyad. A co...
| Hauptverfasser: | , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Frontiers Media S.A.
2012-07-01
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| Schriftenreihe: | Frontiers in Physiology |
| Schlagworte: | |
| Online Zugang: | http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00244/full |