Comparative efficacy of Knema retusa extract delivery via PEG-b-PCL, niosome, and their combination against Acanthamoeba triangularis genotype T4: characterization, inhibition, anti-adhesion, and cytotoxic activity

Comparative efficacy of Knema retusa extract delivery via PEG-b-PCL, niosome, and their combination against Acanthamoeba triangularis genotype T4: characterization, inhibition, anti-adhesion, and cytotoxic activity

Background Acanthamoeba spp. is a waterborne, opportunistic protozoan that can cause amebic keratitis and granulomatous amebic encephalitis. Knema retusa is a native tree in Malaysia, and its extracts possess a broad range of biological activities. Niosomes are non-ionic surfactant-based vesicle for...

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Bibliographic Details
Main Authors: Siriphorn Chimplee, Watcharapong Mitsuwan, Masyitah Zulkifli, Komgrit Eawsakul, Tassanee Ongtanasup, Suthinee Sangkanu, Tooba Mahboob, Sonia M.R. Oliveira, Christophe Wiart, Siva Ramamoorthy, Maria de Lourdes Pereira, Shanmuga Sundar Saravanabhavan, Polrat Wilairatana, Veeranoot Nissapatorn
Format: Article
Language:English
Published: PeerJ Inc. 2024-11-01
Series:PeerJ
Subjects:
Acanthamoeba
Phytoniosome
Niosome
Knema retusa
Nanoparticles
Drug delivery system
Online Access:https://peerj.com/articles/18452.pdf

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https://peerj.com/articles/18452.pdf

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