Deciphering the impact and mechanism of Trikatu, a spices-based formulation on alcoholic liver disease employing network pharmacology analysis and in vivo validation

Deciphering the impact and mechanism of Trikatu, a spices-based formulation on alcoholic liver disease employing network pharmacology analysis and in vivo validation

Trikatu Churna (TC) comprising Zingiber officinale rhizome, Piper longum, and Piper nigrum fruit, is effective in treating liver diseases and has high nutraceutical values. However, the efficacy of TC in treating alcoholic liver disease (ALD) and its mechanism remain largely unknown. This study eval...

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Bibliographic Details
Main Authors: Ruchi Sharma, Mangala Jadhav, Neha Choudhary, Arun Kumar, Abdur Rauf, Rohit Gundamaraju, Abdullah F. AlAsmari, Nemat Ali, Rajeev K. Singla, Rohit Sharma, Bairong Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Nutrition
Subjects:
ethanol-induced hepatotoxicity
hepatoprotective
herbal formulation
network pharmacology
Piper longum
Piper nigrum
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.1063118/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.1063118/full

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