Sequence conservation and functional constraint on intergenic spacers in reduced genomes of the obligate symbiont Buchnera.

Analyses of genome reduction in obligate bacterial symbionts typically focus on the removal and retention of protein-coding regions, which are subject to ongoing inactivation and deletion. However, these same forces operate on intergenic spacers (IGSs) and affect their contents, maintenance, and rat...

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Bibliographic Details
Main Authors: Patrick H Degnan, Howard Ochman, Nancy A Moran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3164680?pdf=render