Capn3 depletion causes Chk1 and Wee1 accumulation and disrupts synchronization of cell cycle reentry during liver regeneration after partial hepatectomy

Capn3 depletion causes Chk1 and Wee1 accumulation and disrupts synchronization of cell cycle reentry during liver regeneration after partial hepatectomy

Abstract Recovery of liver mass to a healthy liver donor by compensatory regeneration after partial hepatectomy (PH) is a prerequisite for liver transplantation. Synchronized cell cycle reentry of the existing hepatocytes after PH is seemingly a hallmark of liver compensatory regeneration. Although...

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Bibliographic Details
Main Authors: Feng Chen, Delai Huang, Hui Shi, Ce Gao, Yingchun Wang, Jinrong Peng
Format: Article
Language:English
Published: SpringerOpen 2020-06-01
Series:Cell Regeneration
Subjects:
Def, Capn3
Chk1
Wee1
Nucleolus
Cell cycle
Liver regeneration
Online Access:http://link.springer.com/article/10.1186/s13619-020-00049-1

Internet

http://link.springer.com/article/10.1186/s13619-020-00049-1

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