2-Aryl-6-Polyfluoroalkyl-4-Pyrones as Promising R<sup>F</sup>-Building-Blocks: Synthesis and Application for Construction of Fluorinated Azaheterocycles

2-Aryl-6-Polyfluoroalkyl-4-Pyrones as Promising R<sup>F</sup>-Building-Blocks: Synthesis and Application for Construction of Fluorinated Azaheterocycles

A convenient and general method for the direct synthesis of 2-aryl-6-(trifluoromethyl)-4-pyrones and 2-aryl-5-bromo-6-(trifluoromethyl)-4-pyrones has been developed on the basis of <i>one-pot</i> oxidative cyclization of (<i>E</i>)-6-aryl-1,1,1-trifluorohex-5-ene-2,4-diones v...

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Bibliographic Details
Main Authors: Sergey A. Usachev, Diana I. Nigamatova, Daria K. Mysik, Nikita A. Naumov, Dmitrii L. Obydennov, Vyacheslav Y. Sosnovskikh
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
β-diketones
4-pyrones
fluorinated heterocycles
regioselective bromination
Online Access:https://www.mdpi.com/1420-3049/26/15/4415

Internet

https://www.mdpi.com/1420-3049/26/15/4415

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