The clinicopathological characteristics of POLE-mutated/ultramutated endometrial carcinoma and prognostic value of POLE status: a meta-analysis based on 49 articles incorporating 12,120 patients

Abstract Objective This study was designed to investigate the frequency and clinicopathological characteristics of POLE-mutated/ultramutated (POLEmut) in endometrial carcinoma (EC) and assess the prognostic values of POLE status. Methods Electronic databases were screened to identify relevant studie...

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Bibliographic Details
Main Authors: Qing Wu, Nianhai Zhang, Xianhe Xie
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-10267-2