Human Mesenchymal Stromal Cells Resolve Lipid Load in High Fat Diet-Induced Non-Alcoholic Steatohepatitis in Mice by Mitochondria Donation

Human Mesenchymal Stromal Cells Resolve Lipid Load in High Fat Diet-Induced Non-Alcoholic Steatohepatitis in Mice by Mitochondria Donation

Mesenchymal stromal cells (MSC) increasingly emerge as an option to ameliorate non-alcoholic steatohepatitis (NASH), a serious disease, which untreated may progress to liver cirrhosis and cancer. Before clinical translation, the mode of action of MSC needs to be established. Here, we established NAS...

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Bibliographic Details
Main Authors: Sandra Nickel, Madlen Christ, Sandra Schmidt, Joanna Kosacka, Hagen Kühne, Martin Roderfeld, Thomas Longerich, Lysann Tietze, Ina Bosse, Mei-Ju Hsu, Peggy Stock, Elke Roeb, Bruno Christ
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
mesenchymal stromal cells
non-alcoholic steatohepatitis
cell transplantation
mitochondria transfer
Online Access:https://www.mdpi.com/2073-4409/11/11/1829

Internet

https://www.mdpi.com/2073-4409/11/11/1829

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