A Novel Effect of Bifemelane, a Nootropic Drug, on Intracellular Ca2+ Levels in Rat Cerebral Astrocytes

Abstract.: We investigated the effects of bifemelane, a nootropic drug, on the intracellular calcium concentration ([Ca2+]i) in rat cerebral astrocytes using a Ca2+ imaging device. At concentrations of 10 – 30 µM, bifemelane induced a slow onset and small increase in the [Ca2+]i, while at higher con...

Full description

Bibliographic Details
Main Authors: Yoshitoku Yoshida, Akira Nakane, Mitsuhiro Morita, Yoshihisa Kudo
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319345244