Stimulation of Cardiomyocyte Proliferation Is Dependent on Species and Level of Maturation

The heart is one of the least regenerative organs. This is in large part due to the inability of adult mammalian cardiomyocytes to proliferate and divide. In recent years, a number of small molecules and molecular targets have been identified to stimulate cardiomyocyte proliferation, including p38 i...

Full description

Bibliographic Details
Main Authors: Dogacan Yücel, Bayardo I. Garay, Rita C. R. Perlingeiro, Jop H. van Berlo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.806564/full