Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) <it>in vitro </it>and Simian Immunodeficiency virus (SIV) <it>ex vivo</it>

<p>Abstract</p> <p>Background</p> <p>WR1065 is the free-thiol metabolite of the cytoprotective aminothiol amifostine, which is used clinically at very high doses to protect patients against toxicity induced by radiation and chemotherapy. In an earlier study we briefly r...

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Bibliographic Details
Main Authors: Borojerdi Jennifer P, Franchini Genoveffa, Hardy Andrew W, Olivero Ofelia A, Poirier Miriam C, Walker Vernon E, Walker Dale M, Shearer Gene M
Format: Article
Language:English
Published: BMC 2009-11-01
Series:AIDS Research and Therapy
Online Access:http://www.aidsrestherapy.com/content/6/1/24