Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation.

The human epidermis is comprised of several layers of specialized epithelial cells called keratinocytes. Normal homoeostasis of the epidermis requires that the balance between keratinocyte proliferation and terminal differentiation be tightly regulated. The mammalian serine/threonine kinases (ROCK1...

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Bibliographic Details
Main Authors: Frances E Lock, Neil A Hotchin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2780731?pdf=render