Novel PDE4 inhibitors derived from Chinese medicine forsythia.

Novel PDE4 inhibitors derived from Chinese medicine forsythia.

Cyclic adenosine monophosphate (cAMP) is a crucial intracellular second messenger molecule that converts extracellular molecules to intracellular signal transduction pathways generating cell- and stimulus-specific effects. Importantly, specific phosphodiesterase (PDE) subtypes control the amplitude...

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Bibliographic Details
Main Authors: Tiffany A Coon, Alison C McKelvey, Nate M Weathington, Rahel L Birru, Travis Lear, George D Leikauf, Bill B Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4280171?pdf=render

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http://europepmc.org/articles/PMC4280171?pdf=render

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