Construction of a bioluminescence-based assay for bitter taste receptors (TAS2Rs)

Abstract In humans, a family of 25 bitter taste receptors (TAS2Rs) mediates bitter taste perception. A common approach to characterize bitter causative agents involves expressing TAS2Rs and the appropriate signal transducers in heterologous cell systems, and monitoring changes in the intracellular f...

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Bibliographic Details
Main Authors: Shi Min Tan, Wei-Guang Seetoh
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21678-3