Cochlear Marginal Cell Pyroptosis Is Induced by Cisplatin via NLRP3 Inflammasome Activation

Cochlear Marginal Cell Pyroptosis Is Induced by Cisplatin via NLRP3 Inflammasome Activation

Better understanding the mechanism of cisplatin-induced ototoxicity is of great significance for clinical prevention and treatment of cisplatin-related hearing loss. However, the mechanism of cisplatin-induced inflammatory response in cochlear stria vascularis and the mechanism of marginal cell (MC)...

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Bibliographic Details
Main Authors: Wenting Yu, Shimin Zong, Peng Zhou, Jiahui Wei, Enhao Wang, Ruijie Ming, Hongjun Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
pyroptosis
cisplatin
marginal cells
NLRP3
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.823439/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.823439/full

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