Human myocardial mitochondrial oxidative capacity is impaired in mild acute heart transplant rejection

Human myocardial mitochondrial oxidative capacity is impaired in mild acute heart transplant rejection

Abstract Aims Acute cellular rejection (ACR) following heart transplantation (HTX) is associated with long‐term graft loss and increased mortality. Disturbed mitochondrial bioenergetics have been identified as pathophysiological drivers in heart failure, but their role in ACR remains unclear. We aim...

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Bibliographic Details
Main Authors: Daniel Scheiber, Elric Zweck, Sophie Albermann, Tomas Jelenik, Maximilian Spieker, Florian Bönner, Patrick Horn, Heinz‐Peter Schultheiss, Ganna Aleshcheva, Felicitas Escher, Udo Boeken, Payam Akhyari, Michael Roden, Malte Kelm, Julia Szendroedi, Ralf Westenfeld
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:ESC Heart Failure
Subjects:
Acute cellular heart transplant rejection
Mitochondrial respiration
Myocardial inflammation
Heart failure
Online Access:https://doi.org/10.1002/ehf2.13607

Internet

https://doi.org/10.1002/ehf2.13607

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