Myricetin alleviated hydrogen peroxide-induced cellular senescence of nucleus pulposus cell through regulating SERPINE1

Abstract Background Myricetin (MYR) is a common plant flavonoid with antioxidant and anticancer properties. However, the anti-aging effect of MYR on nucleus pulposus cells (NPCs) is still unknown. The study aimed to explore the effect of MYR on the senescence of NPCs. Methods Methyl-thiazolyl tetraz...

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Bibliographic Details
Main Authors: Rongsheng Chen, Xiaobo Zhang, Xitian Zhu, Changsheng Wang, Weihong Xu
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-022-03463-0