The hidden sentinel of the skin: An overview on the role of interleukin-13 in atopic dermatitis

The hidden sentinel of the skin: An overview on the role of interleukin-13 in atopic dermatitis

Recent evidence suggests that interleukin (IL)-13 is a crucial cytokine involved in the pathogenesis of atopic dermatitis (AD). It is a central driver of type-2 T-helper inflammation and is overexpressed in lesional skin of AD patients. Upon release in peripheral skin, IL-13 activates its receptors,...

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Bibliographic Details
Main Authors: Maddalena Napolitano, Francesca di Vico, Angelo Ruggiero, Gabriella Fabbrocini, Cataldo Patruno
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Medicine
Subjects:
atopic dermatitis (AD)
interleukin-13
pathogenesis
type 2 inflammation
review
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1165098/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1165098/full

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