Multifunctions of CRIF1 in cancers and mitochondrial dysfunction

Sustaining proliferative signaling and enabling replicative immortality are two important hallmarks of cancer. The complex of cyclin-dependent kinase (CDK) and its cyclin plays a decisive role in the transformation of the cell cycle and is also critical in the initiation and progression of cancer. C...

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Bibliographic Details
Main Authors: Yangzhou Jiang, Yang Xiang, Chuanchuan Lin, Weiwei Zhang, Zhenxing Yang, Lixin Xiang, Yanni Xiao, Li Chen, Qian Ran, Zhongjun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1009948/full