Modeling of Anticancer Sulfonamide Derivatives Lipophilicity by Chemometric and Quantitative Structure-Retention Relationships Approaches

Modeling of Anticancer Sulfonamide Derivatives Lipophilicity by Chemometric and Quantitative Structure-Retention Relationships Approaches

Sulfonamides are a classic group of chemotherapeutic drugs with a broad spectrum of pharmacological action, including anticancer activity. In this work, reversed-phase high-performance liquid chromatography and biomimetic chromatography were applied to characterize the lipophilicity of sulfonamide d...

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Bibliographic Details
Main Authors: Monika Pastewska, Beata Żołnowska, Strahinja Kovačević, Hanna Kapica, Maciej Gromelski, Filip Stoliński, Jarosław Sławiński, Wiesław Sawicki, Krzesimir Ciura
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
sulfonamide derivatives
quantitative structure-retention relationships
lipophilicity
Online Access:https://www.mdpi.com/1420-3049/27/13/3965

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https://www.mdpi.com/1420-3049/27/13/3965

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