Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon
<p>Abstract</p> <p>Background</p> <p>MLL2, an epigenetic regulator in mammalian cells, mediates histone 3 lysine 4 tri-methylation (H3K4me3) through the formation of a multiprotein complex. MLL2 shares a high degree of structural similarity with MLL, which is frequently...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-04-01
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Series: | Cancer Cell International |
Online Access: | http://www.cancerci.com/content/10/1/13 |