Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon

<p>Abstract</p> <p>Background</p> <p>MLL2, an epigenetic regulator in mammalian cells, mediates histone 3 lysine 4 tri-methylation (H3K4me3) through the formation of a multiprotein complex. MLL2 shares a high degree of structural similarity with MLL, which is frequently...

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Bibliographic Details
Main Authors: Ross Jeffrey S, Preet Anju, Ganesan Natarajan, Bartlett Margaret B, Sheehan Christine E, Kallakury Bhaskar V, Natarajan Thanemozhi G, FitzGerald Kevin T
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/10/1/13