Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency

Synthesis of novel 5-HT1A arylpiperazine ligands: Binding data and computer-aided analysis of pharmacological potency

Serotonin receptors modulate numerous behavioral and neuropsychological processes. Therefore, they are the target for the action of many drugs, such as antipsychotics, antidepressants, antiemetics, migraine remedies, and many others. The 5-HT1A receptors have been involved in the pathogenesis and tr...

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Bibliographic Details
Main Authors: Jelena Z. Penjišević, Vladimir B. Šukalović, Sladjana Dukic-Stefanovic, Winnie Deuther-Conrad, Deana B. Andrić, Slađana V. Kostić-Rajačić
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Arabian Journal of Chemistry
Subjects:
Synthesis
Heterocycles
Serotonin-1A receptor
Binding assay
Computer-aided drug analysis
Pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223000977

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http://www.sciencedirect.com/science/article/pii/S1878535223000977

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