Therapeutic potential of Bacillus phage lysin PlyB in ocular infections

ABSTRACT Bacteriophage lytic enzymes (i.e., phage lysins) are a trending alternative for general antibiotics to combat growing antimicrobial resistance. Gram-positive Bacillus cereus causes one of the most severe forms of intraocular infection, often resulting in complete vision loss. It is an inher...

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Bibliographic Details
Main Authors: Md Huzzatul Mursalin, Roger Astley, Phillip S. Coburn, Eddy Bagaruka, Jonathan J. Hunt, Vincent A. Fischetti, Michelle C. Callegan
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00044-23