A Comprehensive Characterization of Monoallelic Expression During Hematopoiesis and Leukemogenesis via Single-Cell RNA-Sequencing

A Comprehensive Characterization of Monoallelic Expression During Hematopoiesis and Leukemogenesis via Single-Cell RNA-Sequencing

Single-cell RNA-sequencing (scRNA-seq) is becoming a powerful tool to investigate monoallelic expression (MAE) in various developmental and pathological processes. However, our knowledge of MAE during hematopoiesis and leukemogenesis is limited. In this study, we conducted a systematic interrogation...

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Bibliographic Details
Main Authors: Ruiqing Fu, Pengfei Qin, Xianghui Zou, Zhangli Hu, Ni Hong, Yun Wang, Wenfei Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
single-cell RNA sequencing
constitutive monoallelic expression
random monoallelic expression
bone marrow mononuclear cells
leukemia
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.702897/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.702897/full

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