Nanoparticle-Induced Augmentation of Neutrophils’ Phagocytosis of Bacteria

Nanoparticle-Induced Augmentation of Neutrophils’ Phagocytosis of Bacteria

Despite the power of antibiotics, bacterial infections remain a major killer, due to antibiotic resistance and hosts with dysregulated immune systems. We and others have been developing drug-loaded nanoparticles that home to the sites of infection and inflammation via engineered tropism for neutroph...

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Bibliographic Details
Main Authors: Kathryn M. Rubey, Alexander R. Mukhitov, Jia Nong, Jichuan Wu, Vera P. Krymskaya, Jacob W. Myerson, G. Scott Worthen, Jacob S. Brenner
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
nanoparticle
nanomedicine
neutrophil
phagocytosis
opsonization
complement
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.923814/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.923814/full

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