2,5-Hexanedione Affects Ovarian Granulosa Cells in Swine by Regulating the <i>CDKN1A</i> Gene: A Transcriptome Analysis

2,5-Hexanedione Affects Ovarian Granulosa Cells in Swine by Regulating the <i>CDKN1A</i> Gene: A Transcriptome Analysis

N-hexane, a common industrial organic solvent, causes multiple organ damage owing to its metabolite, 2,5-hexanedione (2,5-HD). To identify and evaluate the effects of 2,5-HD on sows’ reproductive performance, we used porcine ovarian granulosa cells (pGCs) as a vehicle and carried out cell morphology...

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Bibliographic Details
Main Authors: Yige Chen, Chengcheng Kong, Min Yang, Yangguang Liu, Zheng Han, Liming Xu, Xianrui Zheng, Yueyun Ding, Zongjun Yin, Xiaodong Zhang
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Veterinary Sciences
Subjects:
2,5-Hexanedione(2,5-HD)
granulosa cells
<i>CDKN1A</i>
apoptosis
sow
Online Access:https://www.mdpi.com/2306-7381/10/3/201

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https://www.mdpi.com/2306-7381/10/3/201

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