A double-blind, randomised, placebo-controlled trial comparing intrathecal bupivacaine with bupivacaine plus morphine to reduce delirium in patients with hip fractures—Salmon-Mind trial study protocol

A double-blind, randomised, placebo-controlled trial comparing intrathecal bupivacaine with bupivacaine plus morphine to reduce delirium in patients with hip fractures—Salmon-Mind trial study protocol

Background: Surgical treatment of proximal femur fractures is complicated by postoperative delirium in about one-third of patients. Pain and opioid consumption are modifiable factors that may influence the incidence of delirium.1 An intrathecal injection of morphine may lead to a reduction in postop...

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Bibliographic Details
Main Authors: Aart Jan W. Teunissen, Mark V. Koning, Willem J. Liefers, Dawi v.d. Stap, Gert Roukema, Bart de Bruijn, Charlotte E. Teunissen, Seppe A. Koopman
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:BJA Open
Subjects:
delirium
femur fracture
frailty
intrathecal morphine
Online Access:http://www.sciencedirect.com/science/article/pii/S2772609623000953

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http://www.sciencedirect.com/science/article/pii/S2772609623000953

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