Durability and expansion of neutralizing antibody breadth following Ad26.COV2.S vaccination of mice

Durability and expansion of neutralizing antibody breadth following Ad26.COV2.S vaccination of mice

Abstract Emerging SARS-CoV-2 variants with the potential to escape binding and neutralizing antibody responses pose a threat to vaccine efficacy. We recently reported expansion of broadly neutralizing activity of vaccine-elicited antibodies in humans 8 months following a single immunization with Ad2...

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Bibliographic Details
Main Authors: Shant H. Mahrokhian, Lisa H. Tostanoski, Catherine Jacob-Dolan, Roland C. Zahn, Frank Wegmann, Katherine McMahan, Jingyou Yu, Makda S. Gebre, Esther A. Bondzie, Huahua Wan, Olivia Powers, Tianyi Ye, Julia Barrett, Hanneke Schuitemaker, Dan H. Barouch
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00454-4

Internet

https://doi.org/10.1038/s41541-022-00454-4

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