Aging-Related Accumulation of Truncated Oxidized Phospholipids Augments Infectious Lung Injury and Endothelial Dysfunction via Cluster of Differentiation 36-Dependent Mechanism

Aging-Related Accumulation of Truncated Oxidized Phospholipids Augments Infectious Lung Injury and Endothelial Dysfunction via Cluster of Differentiation 36-Dependent Mechanism

Truncated phospholipid oxidation products (Tr-OxPL) increase in blood circulation with aging; however, their role in the severity of vascular dysfunction and bacterial lung injury in aging groups remains poorly understood. We investigated the effects of six Tr-OxPL species: KOdiA-PC, POVPC, PONPC, P...

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Bibliographic Details
Main Authors: Yunbo Ke, Pratap Karki, Yue Li, Kamoltip Promnares, Chen-Ou Zhang, Thomas L. Eggerman, Alexander V. Bocharov, Anna A. Birukova, Konstantin G. Birukov
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
aging
oxidized phospholipids
bacterial pathogens
lung injury
inflammation
CD36
Online Access:https://www.mdpi.com/2073-4409/12/15/1937

Internet

https://www.mdpi.com/2073-4409/12/15/1937

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