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OBJECTIVES/SPECIFIC AIMS: Pemphigus vulgaris (PV) is a potentially fatal blistering disease caused by autoantibodies to the keratinocyte adhesion protein desmoglein 3. Several other autoimmune diseases have defective B cell tolerance checkpoints, resulting in the accumulation of self-reactive and po...

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Bibliographic Details
Main Authors: Nina Ran, Christoph Ellebrecht, Eun Jung Choi, Aimee Payne
Format: Article
Language:English
Published: Cambridge University Press 2017-09-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866117000516/type/journal_article