Solanum nigrum induces macrophage activation through TLR4-mediated activation of JNK and macrophage autophagy through TLR4-mediated activation of p38 and JNK

In this study, we investigated the effect of Solanum nigrum aerial parts (SNAP) on macrophage activation and macrophage autophagy in RAW264.7 cells. SNAP increased the production of immunostimulatory factors and phagocytosis in RAW264.7 cells. TLR4 inhibition blocked SNAP-mediated production of immu...

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Bibliographic Details
Main Authors: Ju Hyung Yu, Min Yeong Choi, So Jung Park, Na Gyeong Geum, Jae Won Lee, Gwang Hun Park, Hyun Ji Eo, Jin Boo Jeong
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Food and Agricultural Immunology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/09540105.2022.2113507