Identification of novel regulatory cholesterol metabolite, 5-cholesten, 3β,25-diol, disulfate.

Oxysterol sulfation plays an important role in regulation of lipid metabolism and inflammatory responses. In the present study, we report the discovery of a novel regulatory sulfated oxysterol in nuclei of primary rat hepatocytes after overexpression of the gene encoding mitochondrial cholesterol de...

Full description

Bibliographic Details
Main Authors: Shunlin Ren, Jin Koung Kim, Genta Kakiyama, Daniel Rodriguez-Agudo, William M Pandak, Hae-Ki Min, Yanxia Ning
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4114806?pdf=render