Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners.
HSPB5 (also called αB-crystallin) is a ubiquitously expressed small heat shock protein. Mutations in HSPB5 have been found to cause cataract, but are also associated with a subgroup of myofibrillar myopathies. Cells expressing each of these HSPB5 mutants are characterized by the appearance of protei...
Main Authors: | Rasha M Hussein, Ivor J Benjamin, Harm H Kampinga |
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Format: | Article |
Sprog: | English |
Udgivet: |
Public Library of Science (PLoS)
2015-01-01
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Serier: | PLoS ONE |
Online adgang: | https://doi.org/10.1371/journal.pone.0126761 |
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