High-resolution mapping of centromeric protein association using APEX-chromatin fibers

High-resolution mapping of centromeric protein association using APEX-chromatin fibers

Abstract Background The centromere is a specialized chromosomal locus that forms the basis for the assembly of a multi-protein complex, the kinetochore and ensures faithful chromosome segregation during every cell division. The repetitive nature of the underlying centromeric sequence represents a ma...

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Bibliographic Details
Main Authors: Eftychia Kyriacou, Patrick Heun
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Epigenetics & Chromatin
Subjects:
Centromere
Chromatin fibers
CENP-A
CCAN
Kinetochore
APEX
Online Access:http://link.springer.com/article/10.1186/s13072-018-0237-6

Internet

http://link.springer.com/article/10.1186/s13072-018-0237-6

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