Single-cell RNA sequencing reveals metallothionein heterogeneity during hESC differentiation to definitive endoderm

Single-cell RNA sequencing reveals metallothionein heterogeneity during hESC differentiation to definitive endoderm

Differentiation of human pluripotent stem cells towards definitive endoderm (DE) is the critical first step for generating cells comprising organs such as the gut, liver, pancreas and lung. This in-vitro differentiation process generates a heterogeneous population with a proportion of cells failing...

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Bibliographic Details
Main Authors: Junjie Lu, Anna Baccei, Edroaldo Lummertz da Rocha, Christelle Guillermier, Sean McManus, Lydia A. Finney, Cheng Zhang, Matthew L. Steinhauser, Hu Li, Paul H. Lerou
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118300217

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http://www.sciencedirect.com/science/article/pii/S1873506118300217

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