ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment
The late embryonic mouse lens requires the transcription factor ATF4 for its survival although the underlying mechanisms were unknown. Here, RNAseq analysis revealed that E16.5 <i>Atf4</i> null mouse lenses downregulate the mRNA levels of lens epithelial markers as well as known markers...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
|
| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/12/22/2636 |