DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy Outcome

DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy Outcome

There is ample evidence for the essential involvement of DNA repair and DNA damage response in the onset of solid malignancies, including ovarian cancer. Indeed, high-penetrance germline mutations in DNA repair genes are important players in familial cancers: <i>BRCA1</i>, <i>BRCA2...

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Bibliographic Details
Main Authors: Kristyna Tomasova, Andrea Cumova, Karolina Seborova, Josef Horak, Kamila Koucka, Ludmila Vodickova, Radka Vaclavikova, Pavel Vodicka
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
ovarian cancer
DNA repair
carcinogenesis
prognosis
therapy response
Online Access:https://www.mdpi.com/2072-6694/12/7/1713

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https://www.mdpi.com/2072-6694/12/7/1713

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