Effects of OPC-51803, a Novel, Nonpeptide Vasopressin V2-Receptor Agonist, on Micturition Frequency in Brattleboro and Aged Rats

ABSTRACT: We assessed the effects of OPC-51803 ((5R)-2-[1-(2-chloro-4-(1-pyrrolidinyl)benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]-N-isopropylacetamide), a nonpeptide vasopessin V2-receptor agonist, on micturition frequency in female homozygous Brattleboro rats (strain carries hereditary diabet...

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Bibliographic Details
Main Authors: Shigeki Nakamura, Takahiro Hirano, Yoshitaka Yamamura, Shuji Itoh, Kazumi Kondo, Toyoki Mori, Toshimi Kambe
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319325642