Endocannabinoids regulate cocaine-associated memory through brain AEA–CB1R signalling activation

Endocannabinoids regulate cocaine-associated memory through brain AEA–CB1R signalling activation

Objective: Contextual drug-associated memory precipitates craving and relapse in substance users, and the risk of relapse is a major challenge in the treatment of substance use disorders. Thus, understanding the neurobiological underpinnings of how this association memory is formed and maintained wi...

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Bibliographic Details
Main Authors: Hongchun Li, Rong Chen, Yuanyi Zhou, Haichuan Wang, Luqiang Sun, Zhen Yang, Lin Bai, Jie Zhang
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Molecular Metabolism
Subjects:
Cocaine-associated memory
Endocannabinoids
CB1R
Dorsal dentate gyrus
FAAH
AEA
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822001661

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http://www.sciencedirect.com/science/article/pii/S2212877822001661

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