Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety

Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety

A new series of sulfonamides, <b>8a-b, 10, 12</b>, and <b>14a-b</b>, were synthesized by <i>N</i>-sulfonation reaction with sulfonyl chlorides <b>6a-b</b>. Five new series of chalcone-sulfonamide hybrids <b>(16-20)a-f</b> were prepared via...

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Bibliographic Details
Main Authors: Lina Fernanda Castaño, Jairo Quiroga, Rodrigo Abonia, Daniel Insuasty, Oscar M. Vidal, Rosalia Seña, Vivian Rubio, Gloria Puerto, Manuel Nogueras, Justo Cobo, Juan Guzman, Alberto Insuasty, Braulio Insuasty
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
anticancer
antituberculosis
chalcones
molecular hybrids
sulfonamides
Online Access:https://www.mdpi.com/1422-0067/23/20/12589

Internet

https://www.mdpi.com/1422-0067/23/20/12589

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