Comprehensive analysis of M2 macrophage-derived exosomes facilitating osteogenic differentiation of human periodontal ligament stem cells

Abstract Background The role of periodontal ligament stem cells (PDLSCs) and macrophage polarization in periodontal tissue regeneration and bone remodeling during orthodontic tooth movement (OTM) has been well documented. Nevertheless, the interactions between macrophages and PDLSCs in OTM remain to...

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Bibliographic Details
Main Authors: Xian-min Liao, Zheng Guan, Zhen-jin Yang, Li-ya Ma, Ying-juan Dai, Cun Liang, Jiang-tian Hu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-022-02682-5