Chalcone T4 Inhibits RANKL-Induced Osteoclastogenesis and Stimulates Osteogenesis In Vitro

Chalcone T4 Inhibits RANKL-Induced Osteoclastogenesis and Stimulates Osteogenesis In Vitro

Chalcones are phenolic compounds produced during the biosynthesis of flavonoids that have numerous biological activities, including anti-inflammatory, antioxidant and anticancer. In this in vitro study, we investigate a newly synthesized chalcone (Chalcone T4) in the context of bone turnover, specif...

Full description

Bibliographic Details
Main Authors: Iolanda Augusta Fernandes de Matos, Natalie Aparecida Rodrigues Fernandes, Giovani Cirelli, Mariely Araújo de Godoi, Letícia Ribeiro de Assis, Luis Octávio Regasini, Carlos Rossa Junior, Morgana Rodrigues Guimarães-Stabili
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
chalcone
osteoclastogenesis
osteogenesis
intracellular signaling
Online Access:https://www.mdpi.com/1422-0067/24/8/7624

Internet

https://www.mdpi.com/1422-0067/24/8/7624

Similar Items