Solid-phase combinatorial synthesis using microarrays of microcompartments with light-induced on-chip cell screening

The process of drug discovery includes individual synthesis and characterization of drug candidates, followed by a biological screening, which is separated from synthesis in space and time. This approach suffers from low throughput and associated high costs, which in turn lead to inefficiency in the...

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Bibliographic Details
Main Authors: A. Rosenfeld, M. Brehm, A. Welle, V. Trouillet, S. Heissler, M. Benz, P.A. Levkin
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Materials Today Bio
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006419300481