In Vitro Nanobody Library Construction by Using Gene Designated-Region Pan-Editing Technology

Camelid single-domain antibody fragments (nanobodies) are an emerging force in therapeutic biopharmaceuticals and clinical diagnostic reagents in recent years. Nearly all nanobodies available to date have been obtained by animal immunization, a bottleneck restricting the large-scale application of n...

Full description

Bibliographic Details
Main Authors: Zhiyuan Niu, Zhixia Luo, Pengyang Sun, Linwei Ning, Xinru Jin, Guanxu Chen, Changjiang Guo, Lingtong Zhi, Wei Chang, Wuling Zhu
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-01-01
Series:BioDesign Research
Online Access:http://dx.doi.org/10.34133/2022/9823578