In Vitro Nanobody Library Construction by Using Gene Designated-Region Pan-Editing Technology
Camelid single-domain antibody fragments (nanobodies) are an emerging force in therapeutic biopharmaceuticals and clinical diagnostic reagents in recent years. Nearly all nanobodies available to date have been obtained by animal immunization, a bottleneck restricting the large-scale application of n...
Main Authors: | Zhiyuan Niu, Zhixia Luo, Pengyang Sun, Linwei Ning, Xinru Jin, Guanxu Chen, Changjiang Guo, Lingtong Zhi, Wei Chang, Wuling Zhu |
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Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2022-01-01
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Series: | BioDesign Research |
Online Access: | http://dx.doi.org/10.34133/2022/9823578 |
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