Stable silencing of β-lactoglobulin (BLG) gene by lentivirus-mediated RNAi in goat fetal fibroblasts

β-lactoglobulin (BLG), a dominant allergen in goat milk, is difficult to remove by traditional biochemical methods. Its elimination from goat milk by genetic modification therefore poses a major challenge for modern goat breeders. A shRNA targeting BLG mRNA with high interference efficiency was iden...

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Bibliographic Details
Main Authors: Shumin Zhang, Kai Xiong, Zhourui Xie, Wenting Nan, Honglin Liu, Jie Chen
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2012-01-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000400020&lng=en&tlng=en