Tyrosine kinase inhibitor-loaded biomimetic nanoparticles as a treatment for osteosarcoma

Tyrosine kinase inhibitor-loaded biomimetic nanoparticles as a treatment for osteosarcoma

Abstract Small-molecule tyrosine kinase inhibitors (TKIs) represent a potentially powerful approach to the treatment of osteosarcoma (OS). However, dose-limiting toxicity, therapeutic efficacy, and targeting specificity are significant barriers to the use of TKIs in the clinic. Notably among TKIs, p...

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Bibliographic Details
Main Authors: Federica Giordano, Stefania Lenna, Gherardo Baudo, Riccardo Rampado, Matteo Massaro, Enrica De Rosa, April Ewing, Lyazat Kurenbekova, Marco Agostini, Jason T. Yustein, Francesca Taraballi
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Nanotechnology
Subjects:
Tyrosine kinase inhibitor
Ponatinib
Osteosarcoma
Biomimicry
Nanoparticle
Drug delivery system
Online Access:https://doi.org/10.1186/s12645-022-00146-7

Internet

https://doi.org/10.1186/s12645-022-00146-7

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